iZombie

The central conflict between humans and zombies is an explicit social commentary on real-world segregation, discrimination, and hate. The main antagonists are the anti-zombie 'human' hate group, CHICS, led by a white female bigot named Dolly Durkins. The military organization, led by the white male character Major, is shown to be morally compromised by its necessary totalitarian actions. The plot structure centers entirely on systemic oppression.

The established 'human' Seattle/New Seattle society is depicted as fundamentally flawed and hateful, leading to its complete descent into chaos and the breakdown of governmental systems. The central characters ultimately abandon this corrupt civilization, choosing to live as 'immortal recluses' on a remote island. This portrays a deep hostility toward the home culture and its institutions.

Female characters are consistently portrayed as highly capable and effective in leadership roles. Peyton serves as the competent acting Mayor and a prosecutor described as a 'badass.' Liv is the 'Renegade' hero who saves the marginalized. The finale rejects a traditional nuclear family life for the lead couple, instead choosing a non-traditional, immortal existence as 'house parents' to a 'gaggle of Freylich kid zombies and orphans.'

One episode focuses on the murder investigation of a drag queen, requiring the main character Liv to consume the drag queen's brain and embody the personality. This centers an alternative sexual and gender expression, though the overall narrative affirms the normative pairing of the main secondary couple, Clive and Dale.

The character Angus McDonough, a villain, establishes a 'bloodthirsty religious cult of murderous undead' known as 'Brother Love.' He preaches in a church and mimics the Christian sacrament to cynically manipulate his followers for financial and criminal gain. The series directly frames a figure of organized religion as hypocritical and the root of murderous evil.